Anti-endothelial cell antibodies in rheumatic heart disease
نویسندگان
چکیده
منابع مشابه
Anti-endothelial cell antibodies in Behçet's disease.
OBJECTIVE Circulating antibodies that bind to human endothelial cells cultured in vitro have been detected in a variety of diseases, including Behçet's disease. In this disorder the reported prevalence of AECA has varied widely. One likely source of variability is the ELISA assay itself, in which differing conditions and reagents have been used in different reports. METHODS We have re-examine...
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Background/Objective: To clarify the state of different immunologic factors in patients with acute rheumatic fever (ARF) and rheumatic heart disease (RHD) compared to healthy individuals.Patients and Methods: Patients with ARF (#21), patients with RHD six months after the onset of ARF (#19), and healthy children from the same age group with normal physical examination and no history of pharyngi...
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Two observations underlie the hypothesis upon which this study was undertaken. The first is that IgA is the predominant class of immunoglobulins in bronchial secretions (Keimowitz, 1964). Externallysecreted IgA and, to a lesser extent, serum IgA participate in the immunological response to respiratory infection (Rossen, Butler, Waldman, Alford, Hornick, Togo, and Kasel, 1970; Smith, Bellanti, a...
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OUR post-mortem material of fatal cases of cardiac disease in pregnancy consists of rather a small series of twelve patients. Three of these are excluded, because, though the patients suffered from mitral stenosis, they died non-cardiac deaths; one from a cerebral lesion, the second from obstetric shock, and the third, while suffering from active rheumatism, had also pulmonary tuberculosis. Thi...
متن کاملRheumatic heart disease.
Rheumatic heart disease, often neglected by media and policy makers, is a major burden in developing countries where it causes most of the cardiovascular morbidity and mortality in young people, leading to about 250,000 deaths per year worldwide. The disease results from an abnormal autoimmune response to a group A streptococcal infection in a genetically susceptible host. Acute rheumatic fever...
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ژورنال
عنوان ژورنال: Clinical & Experimental Immunology
سال: 2010
ISSN: 0009-9104
DOI: 10.1111/j.1365-2249.2010.04207.x